Rules for losing limbs?

[NecroDancer]

Is there any rules for what happens mechanically if a character losing their arm, eye, leg, etc?

I searched the PHB but I couldn't find anything, is there a sage advice or a paragraph in the DMG that has the rules for limb lose?

(The only reason I'm asking about this is because I want to make an NPC oracle that takes memories, limbs, items, years, etc in exchange for information).

[Easy_Lee]

Undying warlocks can reattach limbs. The spell Regenerate can also regrow limbs. Otherwise, you can't use the limb and the DM decides what that means.

[Waazraath]

I think 2nd edition had critical hit tables that included loosing limbs (including effects). For 5e, besides the obvious (no wielding 2 weapons with only 1 hand), I think it would translate to disadvantage on physical skill checks.

[Millstone85]

Dungeon Master's Guide page 272.