Not according to the devs. Crawford says they balance encounters assuming that PCs are always at full HP.
Ref: https://twitter.com/jeremyecrawford/...964290?lang=enOriginally Posted by JeremyCrawford
Anyway, the point is, the game really does overstate encounter difficulty. Deadly = "not necessarily a curbstomp". IME Deadly x3-4 is approximately the tipping point where good tactics are required to guarantee a win. Fights at Deadly x6-8 are definitely in the monsters' favor, though stilll winnable with good tactics. Medium/Hard/Deadly x1 are still basically guaranteed wins for the PCs unless the DM is deliberately exploiting the holes in the CR system, e.g. by using relatively overpowered monsters like Intellect Devourers and Banshees, or overpowered combos like Yetis and Hobgoblins.