Using Cantrips to break the game more

[Lamech]

Create a small amount of something edible with prestidigitation, and put it in someones food. (Water should work.) In an hour it will be absorbed into their cells, and hopefully DNA. Especially things that get misplaced easily like the protons and electrons. It goes away creating a ton of radicals, breaking bonds whatever; like big dose of radiation.
And no the "no damage shouldn't apply because prestidigitation does no damage. Its the lack of it that does the damage.