Two weeks late, too bad.
When I saw the thread, I was thinking "If you start with Mass Effect, you probably end up as a gaming snob." In a good way. This is top-level quality when it comes to games: Deep story, complex characters, rich world, lots of descisions to make, yet at the same time very linear levels. The only problem is the inventory system, which is waaaay... too complex for way too little gain, but with someone who knows RPGs and this game well to help, it shouldn't be much of a problem. Otherwise, it's really beginner-friendly.
Overall, the series is perfect to show what video games can be. On the downside, it also is what most video games can never come even close to. With this as your baseline, most games will fall short.
With Portal I agree. But mostly it's a case of what you're used to. When I started, I thought shoter on console is a stupid idea. But with some experience, they play just as well. Playing Halo, Bioshock 2, Modern Warfare or Mirror's Edge on console, I never have the feeling that the controlls are insufficient.
That said: Mirror's Edge, big recommendation from me for people who lean towards the more "artsy" games out there, like Mass Effect, Portal, or Shadow of the Colossus.