Interesting choices. I have to ask, why a gun in every slot? The particle rifle alone can handle pretty much everything, with maybe a scope-and-barrel on a pistol for distance precision.
What do you have in your passive skill? I remember as a vanguard I was toting the entire bottom row with no penalty, a tempest or locust, a disciple and a Carnifex. Though I honestly probably should have switched out the disciple; the Carnifex pretty much covered all my non automatic fire needs.