Having seen the first two episodes, my reaction to The Orville is mostly puzzlement. It seems to be Star Trek as lowbrow comedy, played straight, which is kind of bizarre overall. Episode two, in particular, has a story arc that is functionally identical to one that could have (and frankly probably did, by memory of the Trek canon is a little fuzzy) appeared in any mainstream Trek series. There are jokes, and the characters function much more sitcom-style than those in a traditional science fiction drama - which results in them acting both more and less like real people - but there's clearly going to be actual missions and stuff.

It's not bad, just kind of puzzling, and I do hope that the shows finds a groove to meld its influences, since there does seem to be the seed of something there.