And lets also mention Lusamine in Sun and Moon (but not the ultra versions) being an abusive egotistical drug addicted mother who neglected her kids and drove them away due to her obsession with Nihilego. To the point she even dressed Lillie as close to Nihilego as she could and even then could barely stand her. I feel she was the best villain of the franchise due to how realistic and down to earth she was, if being addicted to Space Jellyfish Venom wasn't really out there. But substitute that for any kind of real world substance abuse and you have a villain who is the closest to something anyone could experience. Some prefer Ghetis or Cyrus who have more grand plans with more impact, but there's something about Lusamine simply being an abusive mother with an addiction that makes her stand out to me.