Most of the Tzmisce's mad scientist aspects have been given to the Ordo Dracul, whereas their 'regal lord' aspects have been split between the Ventrue and Daeva. The best way to import the Clan is actually just as a subsect of the Ordo or maybe a Bloodline.

As for Viccissitude, it was already poorly balanced in Masquerade, so importing it wholesale likely wouldn't work. I'd probably start by building it as a bunch of Protean Devotions, or maybe an Ordo Dracul Coil. I do like the idea of a Coil of the Sculptor, beginning with minor temporary changes to yourself, working up to indefinite lengths and more powerful boosts, with Scales allowing you to change others or make weirder changes. One dot would likely be letting you give yourself the Striking Looks merit, while the highest level allows limited movement of Attribute dots (any kind of 'War Form' being redundant with the Protean Discipline). Scales would let you do things like grow claws or wings for a night (or more likely things Protean doesn't do).