Originally Posted by
Segev
In that case, it will depend on how long the alchemy has been around, and how much alchemy in general is stigmatized.
For most people, they'll treat others as whatever they are, physically. Or as what they're presenting as, if they're "pre-transition" and passing effectively. There will still be some awkwardness if the "passing" is revealed to be deceptive, though if the notion of sex changes with alchemy is normalized, then it will likely be treated, at worst, as "well, it's just a matter of time."
One thing to consider is that, if there ARE gender-based roles such as primogenitor, there would be pressure for families in the nobility to ensure a "proper mix" of sexes in their children. The oldest is male. Period. (Or female, if they inherit.) And if something happens to the oldest, and the next-oldest is female, she's expected to transition, unless she has a younger brother to inherit (and even then, there's some tension to make a choice if she's not yet married). Similarly, younger sons who are problematic for inheritance will be turned into girls (or younger daughters into boys, if girls inherit) so they can be married off. It might be that they don't do the transitioning thing unless and until a marriage decision is made, but they will not let birth biology get in the way of a treaty.
To this end, it's quite possible that cross-dressing is common amongst the nobility, especially the children and youths, as they cross-train them in both sets of roles and duties. A proposed marriage between a younger son and an inheriting son might have the younger son not take the potion yet, but still dress in dresses and be expected to act the feminine part up until the betrothal is finalized, at which point the potion is taken and she is a woman. Heck, if a second-born child is already married to a man, but he isn't in line to inherit and she suddenly becomes the heir due to accident befalling her older brother, it might be expected that she and her husband BOTH switch roles and sexes.
So in a sense, this actually could lead to MORE gender dysphoria for socio-political purposes, if the people in question have a personal preference/identity they hold to that clashes with that which their position in society demands.