If Thanos pursues the Stones in the same order, he's only going to have Power by the time he challenges Hela for Space. If the timeline diverges further, he might also have Reality, but Soul, Mind, and Time are either inaccessible or in the hands of the Avengers. That might make it doable, but he's going to have to seriously work at it, and I figure the Queen of Asgard is going to have some very strong home field advantages in a metaphysical sense if nothing else.