Kimiko:
Time slows down for her as her mind analyzes the situation at lightning speed: the recommended countermove for such suicidal attacks is to fall back. That if the enemy is so willing to blow themselves up, don't be in the blast radius. However her pride knew that falling back would be admitting she couldn't capture the enemy that could them much. That she was outplayed. Rush forward, die and fail. Fall back and fail. Kimiko Ishikawa did not tolerate failure. Her eyes narrow in anger as her mind blazes through all the possibilities and available resources around her. There was no time for Usagi's bell genjutsu, that required set up. Yuyuyu did not yet know any genjutsu to put people to sleep. Senko's abilities were so unusual that Kimiko honestly didn't know how to factor them into her plans- she didn't know their full capabilities and limitations. Anyone with more experience who would have prepared solution for this situation was inside or getting help.

So she decided upon a third option.

Kimiko flashed through hand signs shouting
"Kuso! She's starting Last Shout! Paper Clone Jutsu!"
Taking more chakra out of her than most, a clone of Kimiko poofs into existence and speeds for with a body-flicker technique, instantly appearing in front of despair girl and tries to grab the girls hand with her left hand to keep her from forming more hand signs and to use the other one to keep despair girls mouth shut, trying to stop it before she can finish it.