Anechoic chambers. There are actually several, but one particular one is open to the public. Due to how we generally sense, according to reports it's not uncomfortable so much as generally disorienting (I believe most anechoic chambers are dark, due to lighting constraints to keep things in the negative decibel range). From what I've heard, anyone who wants to be in for more than a half hour is highly advised to sit or lie down, and the longest anyone has been in one at one location has been about an hour.
ETA: Also, some people with certain conditions actually find it peaceful, apparently.