If you really wanted to take a blow at someone then you could have a group of environmentalists that think that this crazy new fangled technology is going to destroy the world. These guys may want to go to a magic only system so as not to angry the gods of magic and all that jazz.

I think it would also be interesting to have a place of interest like the Draco Tavern created by Larry Niven. A bar that caters to anything and anyone, especially those that are non-human. This place can have all kinds of crazy drinks and foodstuffs.