Quote Originally Posted by Keld Denar View Post
The only things I can think of that even allow that are the Exotic Weapon Master's Uncanny Blow ability, which isn't accessable until ECL7, and having more than 2 arms and gripping a weapon with 4 arms. I think Diopsid can do that by ECL2, but I'd have to check quick.

EDIT: I just read through the description of Diopsids in the Dragon Compendium, and while it doesn't say anything about using all 4 arms to wield a single weapon, it does say that they can wield a pair of 2-handed weapons. I don't see anything restricting them from using a single 2-handed weapon in all 4 arms, so a Diopsid with a greatsword would get 2x Str bonus, IIRC. Maybe 2.5x...
Diopsids have no special rules for multi-handing a single weapon, so they'd go to the default rules for it, which I believe are that you add .5 Str for each hand after the second, though don't quote me on that. Given that, I think that means a Diopsid would be getting 2.5x Str on a weapon if they quad-handed it.

Yes, those rules are from Savage Species, page 42.